Phospho-NTRK1-Tyr490/NTRK2-Tyr516 Rabbit Monoclonal Antibody
No Size Price Availability  
ARM4914P-21 50ul 1500.00 In Stock
ARM4914P-21 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 4914
Isotype: IgG Swiss Prot: P04629
purity: Affinity purification
Background:
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq
Reactivity Human, Rat
Tested applications WB IP
Clonality Monoclonal Antibody
Calculated MW 140 kDa
Recommended Dilutions
WB 1:1000
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Tyr490 of human TrkA
Storage Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Synonym DKFZp781I14186, MTC, TRK, TRK1, TRKA, p140-TrkA
This product is for research use only, not for diagnostic or therapeutic use!

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