| No | Size | Price | Availability | |
| ARMF037-21 | 50ul | 1500.00 | In Stock |  |
| ARMF037-21 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 54575/54576/54577/54578/54579/54600/54657/54658/54659 |
| Isotype: | / | Swiss Prot: | P22309/Q9HAW8/P35503/P22310/P35504/P19224/Q9HAW7/Q9HAW9/O60656 |
| purity: | Affinity purification |
| Background: |
| Glucuronidation is a major pathway that enhances the elimination of lipophilic xenobiotics and endobiotics to more more water soluble compounds for excretion (1,2). The UDP-glucuronosyltransferase (UGT) superfamily catalyzes the glucuronidation of the glycosyl group of a nucleotide sugar to a variety of endogenous and exogenous compounds. Over 100 UGT mammalian gene products have been described and have been divided into subfamilies based on sequence identities (3). The UGT1 subfamily consists of a number of gene products resulting from alternative splicing. These UGT products can differ in tissue expression and substrate specificity. Also, marked differences in the individual expression of UGT isoforms can account for differences in drug metabolism. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Monoclonal Antibody |
| Calculated MW | 55-60 kDa |
| Recommended Dilutions |
WB 1:1000
|
| Immunogen | A synthetic peptide corresponding to residues near the carboxy terminus of the UGT1A subfamily |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | / |
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