Source: | Rabbit | Gene Id: | 208 |
Isotype: | IgG | Swiss Prot: | P31751 |
purity: | Affinity purification |
Background: |
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq |
Reactivity | Human, Monkey, Mouse, Rat |
Tested applications | IP |
Clonality | Monoclonal Antibody |
Calculated MW | 60 kDa |
Recommended Dilutions | |
Immunogen | A synthetic peptide corresponding to residues of human Akt2 protein |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | PKBB, PKBBETA, PRKBB, RAC-BETA |
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