Source: | Rabbit | Gene Id: | 5970 |
Isotype: | IgG | Swiss Prot: | Q04206 |
purity: | Affinity purification |
Background: |
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. |
Reactivity | Hamster, Human, Monkey, Mouse, Pig, Rat |
Tested applications | WB |
Clonality | Monoclonal Antibody |
Calculated MW | 65 kDa |
Recommended Dilutions |
WB 1:1000
|
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser536 of human NF-κB p65 protein |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | MGC131774, NFKB3, p65 |
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