Source: | Rabbit | Gene Id: | 6197 |
Isotype: | IgG | Swiss Prot: | P51812 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). |
Reactivity | Human, Monkey, Mouse, Rat |
Tested applications | WB |
Clonality | Monoclonal Antibody |
Calculated MW | 90 kDa |
Recommended Dilutions |
WB 1:1000
|
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser227 of human RSK2 |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2 |
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