| No | Size | Price | Availability | |
| ARM4869P-21 | 50ul | 1500.00 | In Stock |  |
| ARM4869P-21 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 4869 |
| Isotype: | IgG | Swiss Prot: | P06748 |
| purity: | Affinity purification |
| Background: |
| Nucleophosmin (NPM1,B23) is a putative ribosome assembly factor with a high affinity for peptides containing nuclear localization signals (NLSs). The transport of proteins across the nuclear envelope is a selective, multistep process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Several cytosolic and nuclear proteins that are central to this process have been identified. The 38 kDa nuclear protein nucleophosmin is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. |
| Reactivity | Human |
| Tested applications | WB FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 38 kDa |
| Recommended Dilutions |
WB 1:1000
FC 1:100
|
| Immunogen | A synthetic phosphopeptide corresponding to residues around Ser4 of human NPM |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | B23, NPM |
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