| No | Size | Price | Availability | |
| HRM4791-21S | 50ul | 1500.00 | In Stock |  |
| HRM4791-21S | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 4791 |
| Isotype: | / | Swiss Prot: | Q00653 |
| purity: | Affinity purification |
| Background: |
| This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants. |
| Reactivity | Human, Monkey |
| Tested applications | WB IHC FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 52 kDa active form. 120 kDa precursor. |
| Recommended Dilutions |
WB 1:1000
IHC 1:300
FC 1:50
|
| Immunogen | A synthetic peptide corresponding to residues at the amino-terminus of human NF-kappaB2 p100/p52 |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | p52, p105, H2TF1, LYT10, LYT-10, NF-kB2 |
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