| No | Size | Price | Availability | |
| ARMM018P-21 | 50ul | 1500.00 | In Stock |  |
| ARMM018P-21 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | / |
| Isotype: | / | Swiss Prot: | / |
| purity: | Affinity purification |
| Background: |
| The 14-3-3 proteins are a highly conserved family of proteins involved in the regulation of cell survival, apoptosis, proliferation and checkpoint control (1-5). Binding of 14-3-3 is mediated through phospho-serine-containing proteins (6). Two different phospho-serine containing motifs are found using a degenerate phospho-serine-oriented peptide library technique, RSXS*XP and RXY/FXS*XP (6). Motif 2 (RXY/FXS*XP) is found in critical regulatory proteins including cdc25A, cdc25B, PKCgamma, IRS-1 and BCR (6). Although Phospho-(Ser) Arg-X-Tyr/Phe-X-pSer Motif Antibody binds 14-3-3 binding motif 2 with no requirement for proline in the +2 position, it provides a powerful tool for the discovery and characterization of potential 14-3-3 binding motif 2-containing proteins or other proteins with the RXY/FXS* motif. |
| Reactivity | Human, Mouse, All |
| Tested applications | WB IP |
| Clonality | Monoclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:1000
|
| Immunogen | Arg-X-Tyr/Phe-X-pSer-containing peptides |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | / |
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