| No | Size | Price | Availability | |
| ARMF021-21 | 50ul | 1500.00 | In Stock |  |
| ARMF021-21 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 1973/1974/9775 |
| Isotype: | IgG | Swiss Prot: | P60842/Q14240/P38919 |
| purity: | Affinity purification |
| Background: |
| A variety of factors contribute to the important biological event of initiation of translation. The eIF4F complex of translation initiation factors binds to the 5' m7 GTP cap to open up the mRNA secondary structure and allow small ribosome subunit binding (1). eIF4A, an eIF4 complex component that acts as an ATP-dependent RNA helicase, unwinds the secondary structure of the 5' mRNA untranslated region to mediate ribosome binding (2,3). In addition, eIF4A has recently been shown to repress Dpp/BMP signalling in a translation-independent manner in Drosophila (4,5). |
| Reactivity | Human, Monkey, Mouse, Rat |
| Tested applications | WB |
| Clonality | Monoclonal Antibody |
| Calculated MW | 48 kDa |
| Recommended Dilutions |
WB 1:1000
|
| Immunogen | A synthetic peptide corresponding to residues surrounding Met316 of human eIF4A protein |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | / |
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