Source: | Rabbit | Gene Id: | 51135 |
Isotype: | IgG | Swiss Prot: | Q9NWZ3 |
purity: | Affinity purification |
Background: |
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. |
Reactivity | Human, (Mouse, Rat, Bovine, Dog) |
Tested applications | WB IP FC |
Clonality | Monoclonal Antibody |
Calculated MW | 55 kDa |
Recommended Dilutions |
WB 1:1000
FC 1:400
|
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Thr345/Ser346 of human IRAK4 protein |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | IPD1, REN64, IRAK-4, NY-REN-64 |
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