Source: | Mouse | Gene Id: | 842 |
Isotype: | IgG1 Kappa | Swiss Prot: | P55211 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms. [provided by RefSeq |
Reactivity | Human |
Tested applications | WB IHC |
Clonality | Monoclonal Antibody |
Calculated MW | 35,37,47 kDa |
Recommended Dilutions |
WB 1:25-1:50
IHC 1:20-1:40
|
Immunogen | A recombinant protein corresponding to 134 amino acid near N-terminus of human CASP9 |
Storage | Store at 4°C on dry atmosphere.After reconstitution with steril distilled water, Store at 4°C for at least two months. |
Synonym | APAF-3, APAF3, CASPASE-9c, ICE-LAP6, MCH6 |
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