Source: | Mouse | Gene Id: | 1759 |
Isotype: | / | Swiss Prot: | Q05193 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq |
Reactivity | Human |
Tested applications | WB IHC ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 100 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:500-1:2000
|
Immunogen | A recombinant protein corresponding to truncated human DNM1 |
Storage | Store at -20°C in ascites.Avoid freeze/thaw cycles. |
Synonym | DNM |
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