| Source: | Mouse | Gene Id: | 1956 |
| Isotype: | IgG1 | Swiss Prot: | P00533 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | IHC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 175 kDa |
| Recommended Dilutions |
IHC 1:50
|
| Immunogen | A synthetic peptide (conjugated with KLH) corresponding to amino acids 985-996 of human EGFR |
| Storage | Store at 4°C in 10 mM potassium phosphate buffer, 150 mM NaCl, 2 mM EDTA, pH 7.25 (1% BSA, 0.1% sodium azide). Do not freeze. |
| Synonym | ERBB, ERBB1, HER1, PIG61, mENA |
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