| No | Size | Price | Availability | |
| AMM867P-11 | 50ul | 1500.00 | In Stock |  |
| AMM867P-11 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 867 |
| Isotype: | IgG1 | Swiss Prot: | P22681 |
| purity: | Affinity purification |
| Background: |
| The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB ELISA |
| Clonality | Monoclonal Antibody |
| Calculated MW | 120 kDa |
| Recommended Dilutions |
WB 1:500
|
| Immunogen | A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y700 of human CBL |
| Storage | Store at -20°C in PBS (50% glycerol, 1 mg/mL BSA, 0.05% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | C-CBL, CBL2, RNF55 |
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