Source: | Mouse | Gene Id: | 835 |
Isotype: | IgG1 | Swiss Prot: | P42575 |
purity: | Affinity purification |
Background: |
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq |
Reactivity | Human |
Tested applications | WB ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 12,14,48 kDa |
Recommended Dilutions |
WB 1:500-1:1000
|
Immunogen | A recombinant protein corresponding to amino acids 32-169 of human CASP2 |
Storage | Store at -20°C in PBS, pH 7.4 (0.1% sodium azide).Avoid freeze/thaw cycles. |
Synonym | CASP-2, ICH-1L, ICH-1L/1S, ICH1, NEDD2 |
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