Source: | Mouse | Gene Id: | 6647 |
Isotype: | IgG1 Kappa | Swiss Prot: | P00441 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq |
Reactivity | Human |
Tested applications | IP |
Clonality | Monoclonal Antibody |
Calculated MW | 18 kDa |
Recommended Dilutions | |
Immunogen | A recombinant protein corresponding to full length human SOD1 |
Storage | Store at -20°C in HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide). Avoid freeze/thaw cycles. |
Synonym | ALS, ALS1, IPOA, SOD, homodimer |
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