| Source: | Mouse | Gene Id: | 4792 |
| Isotype: | IgG1 | Swiss Prot: | P25963 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. |
| Reactivity | Human, Mouse |
| Tested applications | WB ELISA IP |
| Clonality | Monoclonal Antibody |
| Calculated MW | 40 kDa |
| Recommended Dilutions |
WB 1-2 ug/mL
IF 5-10 ug/mL
|
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding S32/S36 of human NFKBIA |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS (0.05% BSA, 0.05% sodium azide). Avoid freeze/thaw cycles. |
| Synonym | IKBA, MAD-3, NFKBI |
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