| No | Size | Price | Availability | |
| AMM110854-31 | 50ul | 1500.00 | In Stock |  |
| AMM110854-31 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 110854(Mouse) |
| Isotype: | IgG2a | Swiss Prot: | P27361 P28482 |
| purity: | Affinity purification |
| Background: |
| Serine/threonine protein phosphatase 2A regulatory subunit 4 (PPP2R4) is one of the constituents of the regulatory subunit B' of PP2A (1). PPP2R4 is also known as the phosphatase activator (PTPA) and known to have the peptidyl prolyl isomerase (PPIase) activity (2-3). PPIases catalyze cis-trans isomerization of peptide bonds of proline residues in the polypeptide chain; this leads to the rapid folding of proteins (2). The ATPase activity of PPP2R4 is required for the phosphotyrosyl phosphatase activity of PP2A (2-4). Evidence suggests that PPP2R4 induces apoptosis independent of the canonical PP2A-mediated pathways (4). |
| Reactivity | Human, Mouse |
| Tested applications | WB |
| Clonality | Monoclonal Antibody |
| Calculated MW | 40 kDa |
| Recommended Dilutions | |
| Immunogen | A recombinant protein specific to the mouse PPP2R4 protein |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | / |
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