Source: | Mouse | Gene Id: | 5591 |
Isotype: | IgG1 | Swiss Prot: | P78527 |
purity: | Affinity purification |
Background: |
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.[supplied by OMIM |
Reactivity | Human, Rat |
Tested applications | IHC IF |
Clonality | Monoclonal Antibody |
Calculated MW | 450 kDa |
Recommended Dilutions |
IHC 1:400
|
Immunogen | Native purified PRKDC from HeLa cells |
Storage | Store at 4°C in 10 mM PBS, pH 7.4 (0.09% sodium azide). |
Synonym | DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 |
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