| No | Size | Price | Availability | |
| AMM5591-13 | 50ul | 1500.00 | In Stock |  |
| AMM5591-13 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 5591 |
| Isotype: | IgG2b | Swiss Prot: | P78527 |
| purity: | Affinity purification |
| Background: |
| The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.[supplied by OMIM |
| Reactivity | Human, Rat |
| Tested applications | IHC IP IF |
| Clonality | Monoclonal Antibody |
| Calculated MW | 450 kDa |
| Recommended Dilutions |
WB 1-2 ug/mL
|
| Immunogen | Native purified PRKDC from HeLa cells |
| Storage | Store at 4°C in 10 mM PBS, pH 7.4 (0.09% sodium azide). |
| Synonym | DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 |
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