CCND1 Mouse Monoclonal Antibody
No Size Price Availability  
AMM595-12 50ul 1500.00 In Stock
AMM595-12 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 595
Isotype: IgG2a Swiss Prot: P24385
purity: Affinity purification
Background:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq
Reactivity Human, Mouse, Orangutan, Rat
Tested applications WB IHC IP
Clonality Monoclonal Antibody
Calculated MW 36 kDa
Recommended Dilutions
Immunogen A recombinant protein corresponding to human CCND1
Storage Store at -20°C in PBS (0.08% sodium azide).Avoid freeze/thaw cycles.
Synonym BCL1, D11S287E, PRAD1, U21B31
This product is for research use only, not for diagnostic or therapeutic use!

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