Source: | Mouse | Gene Id: | 4292 |
Isotype: | IgG2a | Swiss Prot: | P40692 |
purity: | Affinity purification |
Background: |
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined. [provided by RefSeq |
Reactivity | / |
Tested applications | IHC |
Clonality | Monoclonal Antibody |
Calculated MW | 85 kDa |
Recommended Dilutions | |
Immunogen | MLH1 |
Storage | Store at 4°C in PBS, pH 7.4 (protein base, sodium azide). |
Synonym | COCA2, FCC2, HNPCC, HNPCC2, MGC5172, hMLH1 |
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