Source: | Mouse | Gene Id: | 1022 |
Isotype: | IgG2a Kappa | Swiss Prot: | P50613 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq |
Reactivity | Human |
Tested applications | WB ELISA IP |
Clonality | Monoclonal Antibody |
Calculated MW | 40 kDa |
Recommended Dilutions |
WB 1:2000
|
Immunogen | A recombinant His/ABD fusion protein corresponding to amino acids 136-346 of human CDK7 |
Storage | Store at -20°C in HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide). Avoid freeze/thaw cycles. |
Synonym | CAK1, CDKN7, MO15, STK1, p39MO15 |
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