CTNNB1 Mouse Monoclonal Antibody
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AMM1499-11 50ul 1500.00 In Stock
AMM1499-11 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 1499
Isotype: IgG1 Kappa Swiss Prot: P35222
purity: Affinity purification
Background:
β-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the 'contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete.[supplied by OMIM
Reactivity Human
Tested applications WB ELISA IP
Clonality Monoclonal Antibody
Calculated MW 92 kDa
Recommended Dilutions
WB 1:500-1:1000
Immunogen A recombinant His fusion protein corresponding to N-terminus of human CTNNB1
Storage Store at -20°C in HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide). Avoid freeze/thaw cycles.
Synonym CTNNB, DKFZp686D02253, FLJ25606, FLJ37923
This product is for research use only, not for diagnostic or therapeutic use!

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