| No | Size | Price | Availability | |
| AMM84441-11 | 50ul | 1500.00 | In Stock |  |
| AMM84441-11 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 84441 |
| Isotype: | IgG2a Kappa | Swiss Prot: | Q8IZL2 |
| purity: | Affinity purification |
| Background: |
| Mastermind-like (MAML) family of proteins are homologs of Drosophila Mastermind. The family is composed of three members in mammals: MAML1, MAML2, and MAML3. MAML proteins form complexes with the intracellular domain of Notch (ICN) and the transcription factor CSL (RBP-Jκ) to regulate Notch target gene expression. MAML1 also interacts with myocyte enhancer factor 2C (MEF2C) to regulate myogenesis. MAML2 is frequently found to be fused with Mucoepidermoid carcinoma translocated gene 1 (MECT1, also know as WAMTP1 or TORC1) in patients with mucoepidermoid carcinomas and Warthin's tumors. |
| Reactivity | Human |
| Tested applications | WB ELISA |
| Clonality | Monoclonal Antibody |
| Calculated MW | 160 kDa |
| Recommended Dilutions | |
| Immunogen | MAML2 (NP_115803, 796 aa ~ 894 aa) partial recombinant protein with GST tag |
| Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Synonym | DKFZp686N0150, KIAA1819, MAM-3, MAM2, MAM3, MGC176701, MLL-MAML2 |
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