Source: | Rabbit | Gene Id: | 64236 |
Isotype: | IgG | Swiss Prot: | Q96JY6 |
purity: | Affinity purification |
Background: |
PDLIM2, also known as Mystique, contains an amino-terminal PDZ domain and a carboxy-terminal LIM domain. PDLIM2 was orginally found to be associated with cytoskeletal proteins in epithelial cells to promote cell attachment and migration. Subsequent studies have shown that PDLIM2 can also inhibit NF-κB activity by acting as a nuclear ubiquitin E3 ligase for p65. PDLIM2 is suppressed in cancer cell lines by DNA methylation. Expression of PDLIM2 can inhibit anchorage-independent growth and tumor formation. |
Reactivity | Human |
Tested applications | WB ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 37.50 kDa |
Recommended Dilutions | |
Immunogen | A synthetic peptide of human PDLIM2 is used for rabbit immunization |
Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Synonym | FLJ34715, MYSTIQUE, SLIM |
沪ICP备15003525号 Copyright ©, 2013-2019, Yihyson All Rights Reserved.