CAB39 Rabbit Monoclonal Antibody
No Size Price Availability  
ARM51719-11 50ul 1500.00 In Stock
ARM51719-11 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 51719
Isotype: IgG Swiss Prot: Q9Y376
purity: Affinity purification
Background:
AMPK (AMP-activated protein kinase) is a key cellular component that regulates energy homeostasis. When the AMP/ATP ratio is increased due to energy depletion, AMPK is phosphorylated at its α1 and α2 catalytic subunits and activated. Studies showed that the tumor suppressor LKB1 phosphorylates and activates AMPK in mammals. MO25α (mouse protein 25α), also called CAB39 (calcium binding protein 39), is a component of the LKB1 complex in vivo. MO25α/CAB39 does not directly interact with LKB1; instead, it is physically associated with STRADα. Together MO25α/CAB39 and STRADα help anchor LKB1 in the cytoplasm. MO25α/CAB39 stablizes the LKB1-STRADα complex and further increases the catalytic activity of LKB1.
Reactivity Human
Tested applications WB ELISA
Clonality Monoclonal Antibody
Calculated MW 39 kDa
Recommended Dilutions
Immunogen A synthetic peptide of human CAB39 is used for rabbit immunization
Storage Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Synonym CGI-66, FLJ22682, MO25
This product is for research use only, not for diagnostic or therapeutic use!

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