| No | Size | Price | Availability | |
| AMM25937-11 | 50ul | 1500.00 | In Stock |  |
| AMM25937-11 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 25937 |
| Isotype: | IgG2a Kappa | Swiss Prot: | Q9GZV5 |
| purity: | Affinity purification |
| Background: |
| TAZ is a transcriptional co-activator with a PDZ-binding motif that is regulated by its interaction with 14-3-3 proteins (1). TAZ shares homology with the WW domain of Yes-associated protein (YAP). TAZ is proposed to modulate the switch between proliferation and differentiation of mesenchymal stem cells (MSC) via interaction with transcription factors Runx2 and PPARγ. This process is critical to normal tissue development and the prevention of tumor formation. Due to its role in determination of MSC fate, TAZ may have clinical relevance to several human diseases caused by an imbalance of MSC differentiation. TAZ appears to be negatively regulated by LATS tumor suppressor kinase, a component of the Hippo pathway that controls tissue growth and tumor development. |
| Reactivity | Human |
| Tested applications | WB IHC S-ELISA ELISA |
| Clonality | Monoclonal Antibody |
| Calculated MW | 50 kDa |
| Recommended Dilutions | |
| Immunogen | WWTR1 (NP_0562871, 201 aa ~ 300 aa) partial recombinant protein with GST tag |
| Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Synonym | DKFZp586I1419, TAZ |
沪ICP备15003525号 Copyright ©, 2013-2019, Yihyson All Rights Reserved. 
