Source: | Rabbit | Gene Id: | 23765 |
Isotype: | IgG | Swiss Prot: | Q96F46 |
purity: | Affinity purification |
Background: |
Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. |
Reactivity | Human |
Tested applications | WB ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 120-170 kDa |
Recommended Dilutions | |
Immunogen | A synthetic peptide of human IL17RA is used for rabbit immunization |
Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Synonym | CD217, CDw217, IL-17RA, IL17R, MGC10262, hIL-17R |
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