Source: | Mouse | Gene Id: | 23411 |
Isotype: | IgG1 Kappa | Swiss Prot: | Q96EB6 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. |
Reactivity | Human |
Tested applications | WB S-ELISA ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 120 kDa |
Recommended Dilutions | |
Immunogen | SIRT1 (AAH12499, 456 aa ~ 555 aa) partial recombinant protein with GST tag |
Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Synonym | SIR2L1 |
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