Source: | Rabbit | Gene Id: | 22861 |
Isotype: | IgG | Swiss Prot: | Q9C000 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. |
Reactivity | Human |
Tested applications | WB ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 70, 165 kDa |
Recommended Dilutions | |
Immunogen | A synthetic peptide of human NLRP1 is used for rabbit immunization |
Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Synonym | CARD7, CLR17.1, DEFCAP, DEFCAP-L/S, DKFZp586O1822, KIAA0926, NAC, NALP1, PP1044, SLEV1, VAMAS1 |
沪ICP备15003525号 Copyright ©, 2013-2019, Yihyson All Rights Reserved.