Source: | Rabbit | Gene Id: | 10670 |
Isotype: | IgG | Swiss Prot: | Q7L523 |
purity: | Affinity purification |
Background: |
The mTORC1 kinase complex is a critical regulator of cell growth. Its activity is modulated by energy levels, growth factors, and amino acids via signaling through Akt, MAPK, and AMPK pathways. Recent studies found that the four related GTPases, RagA, RagB, RagC, and RagD, interact with raptor within the mTORC1 complex. These interactions are both necessary and sufficient for mTORC1 activation in response to amino acid signals. |
Reactivity | Human |
Tested applications | WB ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 30 kDa |
Recommended Dilutions | |
Immunogen | A synthetic peptide of human RRAGA is used for rabbit immunization |
Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Synonym | FIP-1, FIP1, RAGA |
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