| No | Size | Price | Availability | |
| AMM10411-11 | 50ul | 1500.00 | In Stock |  |
| AMM10411-11 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 10411 |
| Isotype: | IgG2a Kappa | Swiss Prot: | O95398 |
| purity: | Affinity purification |
| Background: |
| EPAC1 and EPAC2 (exchange proteins activated by cyclic AMP) are guanine nucleotide exchange factors (GEFs) that catalyze the exchange of GDP for GTP, activating Rap1 and Rap2 small GTPases. Rap activation by EPAC is cAMP-dependent and mediates cAMP signaling in part through protein kinase A (PKA). EPAC signaling plays a significant role in a number of cellular processes including migration and focal adhesion formation, exocytosis, insulin signaling, axon growth and guidance and neurotransmitter release. |
| Reactivity | Human |
| Tested applications | WB S-ELISA ELISA |
| Clonality | Monoclonal Antibody |
| Calculated MW | 100 kDa |
| Recommended Dilutions | |
| Immunogen | RAPGEF3 (AAH17728, 772 aa ~ 881 aa) partial recombinant protein with GST tag |
| Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Synonym | CAMP-GEFI, EPAC, EPAC1, HSU79275, MGC21410, bcm910 |
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