Source: | Rabbit | Gene Id: | 7405 |
Isotype: | IgG | Swiss Prot: | Q9P2Y5 |
purity: | Affinity purification |
Background: |
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. |
Reactivity | Human |
Tested applications | WB ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 90 kDa |
Recommended Dilutions | |
Immunogen | A synthetic peptide of human UVRAG is used for rabbit immunization |
Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Synonym | DHTX, p63 |
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