NR2F1 Rabbit Monoclonal Antibody
No Size Price Availability  
ARM7025-11 50ul 1500.00 In Stock
ARM7025-11 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 7025
Isotype: IgG Swiss Prot: P10589
purity: Affinity purification
Background:
Chicken ovalbumin upstream promoter transcription factor (COUP-TF) belongs to the NR2 subfamily of the nuclear hormone receptor family. COUP-TFI and COUP-TFII are two of the well-characterized members in the NR2 subfamily. These two members are highly conserved in their two zinc-finger DNA binding domains (DBD) and the ligand binding domain (LBD), and function as repressors or activators of downstream target genes to regulate different biological processes. COUP-TFI and II bind to 5'-AGGTCA-3' motif palindromes, either directly or indirectly, through heterodimer formation with other proteins (e.g. RXRs) to regulate downstream target gene expression. COUP-TFI is involved in neuronal development, tissue patterning, and differentiation. COUP-TFII has been shown to be involved in angiogenesis, glucose homeostasis, and mesenchymal cell commitment.
Reactivity Human
Tested applications WB ELISA
Clonality Monoclonal Antibody
Calculated MW 47 kDa
Recommended Dilutions
Immunogen A synthetic peptide of human NR2F1 is used for rabbit immunization
Storage Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Synonym COUP-TFI, EAR-3, EAR3, ERBAL3, NR2F2, SVP44, TCFCOUP1, TFCOUP1
This product is for research use only, not for diagnostic or therapeutic use!

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