STAT5A Mouse Monoclonal Antibody
No Size Price Availability  
AMM6776-11 50ul 1500.00 In Stock
AMM6776-11 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 6776
Isotype: IgG1 Kappa Swiss Prot: P42229
purity: Affinity purification
Background:
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells.
Reactivity Human
Tested applications WB ELISA
Clonality Monoclonal Antibody
Calculated MW 90 kDa
Recommended Dilutions
Immunogen STAT5A (AAH27036, 1 aa ~ 104 aa) partial recombinant protein with GST tag
Storage Store at -20°C or lower in ascites fluid. Avoid freeze/thaw cycles.
Synonym MGF, STAT5
This product is for research use only, not for diagnostic or therapeutic use!

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