Source: | Mouse | Gene Id: | 5591 |
Isotype: | IgG2a Kappa | Swiss Prot: | P78527 |
purity: | Affinity purification |
Background: |
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku, which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties. |
Reactivity | Human |
Tested applications | WB IHC S-ELISA ELISA IF |
Clonality | Monoclonal Antibody |
Calculated MW | 450 kDa |
Recommended Dilutions | |
Immunogen | PRKDC (NP_008835, 4019 aa ~ 4128 aa) partial recombinant protein with GST tag |
Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Synonym | DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 |
沪ICP备15003525号 Copyright ©, 2013-2019, Yihyson All Rights Reserved.