POU5F1 Mouse Monoclonal Antibody
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AMM5460-14 50ul 1500.00 In Stock
AMM5460-14 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 5460
Isotype: IgG2b Kappa Swiss Prot: Q01860
purity: Affinity purification
Background:
This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
Reactivity Human
Tested applications WB ELISA
Clonality Monoclonal Antibody
Calculated MW 18.3 kDa
Recommended Dilutions
Immunogen POU5F1 (AAH20712, 81 aa ~ 164 aa) full length recombinant protein with GST tag
Storage Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Synonym MGC22487, OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4
This product is for research use only, not for diagnostic or therapeutic use!

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