Source: | Mouse | Gene Id: | 5430 |
Isotype: | IgG2b Kappa | Swiss Prot: | P24928 |
purity: | Affinity purification |
Background: |
This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq |
Reactivity | Human |
Tested applications | WB S-ELISA ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 250 kDa |
Recommended Dilutions | |
Immunogen | POLR2A (NP_000928, 1 aa ~ 110 aa) partial recombinant protein with GST tag |
Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Synonym | MGC75453, POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1 |
沪ICP备15003525号 Copyright ©, 2013-2019, Yihyson All Rights Reserved.