Source: | Mouse | Gene Id: | 4744 |
Isotype: | IgG2a Kappa | Swiss Prot: | P12036 |
purity: | Affinity purification |
Background: |
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. |
Reactivity | Human |
Tested applications | WB S-ELISA ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 180-220 kDa |
Recommended Dilutions | |
Immunogen | NEFH (NP_066554, 263 aa ~ 363 aa) partial recombinant protein with GST tag |
Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Synonym | NFH |
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