Source: | Mouse | Gene Id: | 3718 |
Isotype: | IgG2a Kappa | Swiss Prot: | P52333 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). |
Reactivity | Human |
Tested applications | WB ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 115 kDa |
Recommended Dilutions | |
Immunogen | JAK3 (AAH28068, 1 aa ~ 619 aa) full-length recombinant protein with GST tag |
Storage | Store at -20°C or lower in ascites fluid. Avoid freeze/thaw cycles. |
Synonym | JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK |
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