INCENP Rabbit Monoclonal Antibody
No Size Price Availability  
ARM3619-11 50ul 1500.00 In Stock
ARM3619-11 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 3619
Isotype: IgG Swiss Prot: Q9NQS7
purity: Affinity purification
Background:
In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins. The constitutive proteins include CENPA (centromere protein A), CENPB, CENPC1, and CENPD. The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle. These include CENPE; MCAK; KID; cytoplasmic dynein; CliPs and CENPF/mitosin. The inner centromere proteins (INCENPs), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis.
Reactivity Human
Tested applications WB ELISA
Clonality Monoclonal Antibody
Calculated MW 140 kDa
Recommended Dilutions
Immunogen A synthetic peptide of human INCENP is used for rabbit immunization
Storage Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Synonym FLJ31633, MGC111393
This product is for research use only, not for diagnostic or therapeutic use!

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