CDK4 Mouse Monoclonal Antibody
No Size Price Availability  
AMM1019-12 50ul 1500.00 In Stock
AMM1019-12 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 1019
Isotype: IgG2a Kappa Swiss Prot: P11802
purity: Affinity purification
Background:
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.
Reactivity Human
Tested applications WB S-ELISA ELISA
Clonality Monoclonal Antibody
Calculated MW 33.7 kDa
Recommended Dilutions
Immunogen CDK4 (AAH03644, 1 aa ~ 303 aa) full-length recombinant protein with GST tag
Storage Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Synonym CMM3, MGC14458, PSK-J3
This product is for research use only, not for diagnostic or therapeutic use!

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