CDH1 Mouse Monoclonal Antibody
No Size Price Availability  
AMM999-11 50ul 1500.00 In Stock
AMM999-11 100ul 2000.00 In Stock
  • Details
  • FAQs
  • Manual
Source: Mouse Gene Id: 999
Isotype: IgG1 kappa Swiss Prot: P12830
purity: Affinity purification
Background:
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
Reactivity Human
Tested applications WB IHC S-ELISA ELISA PLA
Clonality Monoclonal Antibody
Calculated MW 135 kDa
Recommended Dilutions
Immunogen CDH1 (NP_004351, 381 aa ~ 480 aa) partial recombinant protein with GST tag
Storage Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Synonym Arc-1, CD324, CDHE, ECAD, LCAM, UVO
This product is for research use only, not for diagnostic or therapeutic use!

backtop
QQ
service center
Contact Us