Source: | Rabbit | Gene Id: | 864 |
Isotype: | IgG | Swiss Prot: | Q13761 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. |
Reactivity | Human |
Tested applications | WB ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 43-48 kDa |
Recommended Dilutions | |
Immunogen | A synthetic peptide of human RUNX3 is used for rabbit immunization |
Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Synonym | AML2, CBFA3, FLJ34510, MGC16070, PEBP2aC |
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