| No | Size | Price | Availability | |
| ARM487-11 | 50ul | 1500.00 | In Stock |  |
| ARM487-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 487 |
| Isotype: | IgG | Swiss Prot: | O14983 |
| purity: | Affinity purification |
| Background: |
| This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in two transcript variants encoding different isoforms. |
| Reactivity | Human |
| Tested applications | WB ELISA |
| Clonality | Monoclonal Antibody |
| Calculated MW | 100 kDa |
| Recommended Dilutions | |
| Immunogen | A synthetic peptide of human ATP2A1 is used for rabbit immunizationCustomer or Abnova will decide on the preferred peptide sequence |
| Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Synonym | ATP2A, SERCA1 |
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