Source: | Mouse | Gene Id: | 208 |
Isotype: | IgG1 Kappa | Swiss Prot: | P31751 |
purity: | Affinity purification |
Background: |
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB S-ELISA ELISA IF |
Clonality | Monoclonal Antibody |
Calculated MW | 60 kDa |
Recommended Dilutions | |
Immunogen | AKT2 (AAA58364, 100 aa ~ 189 aa) partial recombinant protein with GST tag |
Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Synonym | PKBB, PKBBETA, PRKBB, RAC-BETA |
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