Source: | Mouse | Gene Id: | 842 |
Isotype: | IgG1 kappa | Swiss Prot: | P55211 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Monoclonal Antibody |
Calculated MW | 47 kDa(H),51 kDa(R,M) |
Recommended Dilutions |
WB 0.736111
|
Immunogen | A synthetic peptide derived from human CASP9 |
Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Synonym | APAF-3, APAF3, CASPASE-9c, ICE-LAP6, MCH6 |
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