CD86 Mouse Monoclonal Antibody
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AMM942-61 50ul 1500.00 In Stock
AMM942-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 942
Isotype: IgG1 Swiss Prot: P42081
purity: Affinity chromatography
Background:
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.Tissue specificity: Expressed by activated B-lymphocytes and monocytes.
Reactivity Human
Tested applications WB ELISA
Clonality Monoclonal Antibody
Calculated MW 52 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen A purified recombinant fragment of human CD86 expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym B70, B7-2, LAB72, CD28LG2, MGC34413, CD86
This product is for research use only, not for diagnostic or therapeutic use!

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