| No | Size | Price | Availability | |
| AMM2891-61 | 50ul | 1500.00 | In Stock |  |
| AMM2891-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 2891 |
| Isotype: | IgG1 | Swiss Prot: | P42262 |
| purity: | Affinity chromatography |
| Background: |
| Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene. |
| Reactivity | Human |
| Tested applications | WB ELISA FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 99 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
FC 1:200-1:400
|
| Immunogen | A purified recombinant fragment of human GRIA2 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | GluA2, GluR2, gluR-B, GluR-K2 |
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